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Roups (n = 7 per group): 1) CFA + Vehicle + Sham EA, 2) CFA + Vehicle + EA, 3) CFA + Astressin (Sigma) + Sham EA and 4) CFA + Astressin + EA. The paw thickness was measured with the same Laser Sensor. A 2 mg/ml concentration of astressin was dissolved in saline, and 0.2 mg/kg of astressin or vehicle was injected (i.v.) 5 min before each of two 10 Hz EA treatments. Experiment 4 was to determine whe
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Roups (n = 7 per group): 1) CFA + Vehicle + Sham EA, 2) CFA + Vehicle + EA, 3) CFA + Astressin (Sigma) + Sham EA and 4) CFA + Astressin + EA. The paw thickness was measured with the same Laser Sensor. A 2 mg/ml concentration of astressin was dissolved in saline, and 0.2 mg/kg of astressin or vehicle was injected (i.v.) 5 min before each of two 10 Hz EA treatments. Experiment 4 was to determine whe
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Roups (n = 7 per group): 1) CFA + Vehicle + Sham EA, 2) CFA + Vehicle + EA, 3) CFA + Astressin (Sigma) + Sham EA and 4) CFA + Astressin + EA. The paw thickness was measured with the same Laser Sensor. A 2 mg/ml concentration of astressin was dissolved in saline, and 0.2 mg/kg of astressin or vehicle was injected (i.v.) 5 min before each of two 10 Hz EA treatments. Experiment 4 was to determine whe
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Roups (n = 7 per group): 1) CFA + Vehicle + Sham EA, 2) CFA + Vehicle + EA, 3) CFA + Astressin (Sigma) + Sham EA and 4) CFA + Astressin + EA. The paw thickness was measured with the same Laser Sensor. A 2 mg/ml concentration of astressin was dissolved in saline, and 0.2 mg/kg of astressin or vehicle was injected (i.v.) 5 min before each of two 10 Hz EA treatments. Experiment 4 was to determine whe
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Al needle [12]. Inflammation appeared within 2 h of the injection and peaked between 6?4 h. PWL was tested with a previously described method [12,13]. Each rat was placed under an inverted clear plastic chamber on the glass surface of the Paw Thermal Stimulator System (UCSD, San Diego) and allowed to acclimatize for 30 min before the test. A radiant heat stimulus was applied to the plantar surface
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Al needle [12]. Inflammation appeared within 2 h of the injection and peaked between 6?4 h. PWL was tested with a previously described method [12,13]. Each rat was placed under an inverted clear plastic chamber on the glass surface of the Paw Thermal Stimulator System (UCSD, San Diego) and allowed to acclimatize for 30 min before the test. A radiant heat stimulus was applied to the plantar surface
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Ffects in patients with various inflammatory diseases [1]. Studies demonstrate that EA significantly inhibits complete Freund's adjuvant (CFA)-induced hind paw inflammation and hyperalgesia in a rat model [2,3]. However, the underlying mechanisms of acupuncture are still not completely understood. We recently demonstrated that EA significantly increased plasma corticosterone levels in rats with hi
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Ffects in patients with various inflammatory diseases [1]. Studies demonstrate that EA significantly inhibits complete Freund's adjuvant (CFA)-induced hind paw inflammation and hyperalgesia in a rat model [2,3]. However, the underlying mechanisms of acupuncture are still not completely understood. We recently demonstrated that EA significantly increased plasma corticosterone levels in rats with hi